Showing study: Oral Budesonide for Active Crohn's Disease (Greenberg et al.)






Study overview

  • Figure shows absolute benefit/risk. This is calculated by assessing benefit/risk of study drug against placebo, except where stated
  • Double-blind, multicenter trial of 258 patients with CDAI > 200 were randomly assigned to receive placebo or one of three doses of budesonide (3, 9, or 15 mg daily)
  • Primary outcome measure was clinical remission, as defined by a score of 150 or less on the Crohn's disease activity index
  • The proportion of patients with corticosteroid-associated effects was not significantly different between the groups: 38 percent in the 15-mg group, 26 percent in the 9-mg group, 15 percent in the 3-mg group, and 26 percent in the placebo group

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